10-Hydroxycamptothecin(micro-alkaloid,camptothecine )
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Product Name: 10-Hydroxycamptothecin
Specification: 98%10-Hydroxycamptothecin
Detection method: HPLC
Molecular formula: C20H16N2O5
Molucular weight: 364.36
Formulation: light yellow white crystalline powder
Description:
10-hydroxycamptothecin is the derivative of camptothecine that is a micro-alkaloid from camptotheca Acuminate (a tree native to mainland China). is a kind of pharmaceutical intermediate, an alkaloid originally isolated from the Camptotheca acuminata, exerted inhibitory effects on DNA topoisomerase Ⅰ (Topo Ⅰ) and has anticancer activity in vitro and in vivo. It can also induce differentiation of leukemia MELC and HL-60 cells. The purpose of this study is to investigate the proliferation-inhibiting and differentiation-inducing actions of HCPT on human hepatoma Hep G2 cells.
[Date:2008-12-02]
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