Product Name:     Aloeemodin   (  Aloe vera  extract)
        
specification:    99%Aloeemodin
         
Detection method:    HPLC
         
Botanical Name:   Aloe barbadensis Miller  /Rheum palmatum L

Molecular formula: C15H10O5

Molecular weight: 270.24

Formulation:  White powder  

Description:

aloe-emodin (AE), a hydroxyanthraquinone present in Aloe vera leaves, has a specific in vitro and in vivo antineuroectodermal tumor activity. The growth of human neuroectodermal tumors is inhibited in mice with severe combined immunodeficiency without any appreciable toxic effects on the animals. The compound does not inhibit the proliferation of normal fibroblasts nor that of hemopoietic progenitor cells. The cytotoxicity mechanism consists of the induction of apoptosis, whereas the selectivity against neuroectodermal tumor cells is founded on a specific energy-dependent pathway of drug incorporation. Taking into account its unique cytotoxicity profile and mode of action, AE might represent a conceptually new lead antitumor drug.